Murray, who is now the Spurs' starting point guard following Popovich's decision to bench Tony Parker, previously referred to James as his "big bro" in an Instagram post a few weeks ago.
And it appears the feeling is mutual for James, since he lovingly called the 21-year-old point guard "the kid" during Tuesday's shootaround.
#✌🏾☝🏾👌🏾 NEWS: #Cavs @KingJames had nothing but compliments for #Spurs, @tonyparker HOF career & rising star @DejounteMurray. LeBron said Dejounte needs to 'seize the opportunity' & 'listen to Pop...he knows what the hell he's doing.' (h/t @markmendez) #KSATsports #GoSpursGo pic.twitter.com/oB6NnLRGzB— Adrian Garcia (@KSATadrian) January 23, 2018
"Trust The Process, Keep Learning And Get Better Every Single Day" pic.twitter.com/rnCnEAailq— Dejounte Murray (@DejounteMurray) December 25, 2016
But James' confidence in Murray soon turned to praise for Coach Pop. He said Murray's best bet would be to follow advice from the legendary coach, while also offering up his own bit of wisdom.
"He knows what the hell he's doing," James told reporters before the game, according to KSAT. "Every game, every opportunity, you just think it could be your last and that's how you don't take things for granted."
James seems to follow his own advice. While the Cavaliers lost to the Spurs Tuesday night, James became the youngest player in NBA history to reach 30,000 points. Of course, Popovich congratulated James on the feat as well, though he told reporters it wasn't their business what he said.
"He's one of my favorite guys ever," James told KSAT. "I love everything that Pop represents both on and off the floor."
Check out all he had to say about Popovich, the Spurs franchise and earning his new record.
#✌🏾☝🏾👌🏾: #Cavs #LeBron James (@KingJames) thanked #Spurs fans & #SpursNation for the standing ovation when he became the youngest player in #NBA history to reach 30,000 pts tonight. He also made time to share how much he admires #Popovich #KSATnews #GoSpursGo #KSATsports pic.twitter.com/VTuNzhIZRS— Adrian Garcia (@KSATadrian) January 24, 2018